Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.32 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
| ▸ | USP5 | P45974 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925406 | 1.00 | ACMSD (0.32) | ACMSDQDPRKDM1AKCNH2KDM1B | |
| SCHEMBL8728306 | 0.85 | ESR2 (0.33) | ACMSDUSP5HDAC6 | |
| SCHEMBL8728303 | 0.85 | ESR2 (0.33) | ACMSDUSP5HDAC6 | |
| SCHEMBL8728309 | 0.85 | ESR2 (0.33) | ACMSDUSP5HDAC6 | |
| SCHEMBL7767252 | 0.77 | CYP2C9 (0.42) | — | |
| SCHEMBL7767255 | 0.77 | CYP2C9 (0.42) | — | |
| SCHEMBL7767250 | 0.77 | CYP2C9 (0.42) | — | |
| SCHEMBL7767257 | 0.77 | CYP2C9 (0.42) | — | |
| SCHEMBL7762634 | 0.76 | HTR2A (0.40) | KDM1AKCNH2KDM1BUSP5HDAC6 | |
| SCHEMBL8732254 | 0.73 | ESR2 (0.33) | ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |