Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.33 |
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728309 | 1.00 | ESR2 (0.33) | ESR2ESR1CYP3A4CYP2C9USP5 | |
| SCHEMBL8728303 | 1.00 | ESR2 (0.33) | ESR2ESR1CYP3A4CYP2C9USP5 | |
| SCHEMBL8732250 | 0.89 | ESR2 (0.33) | ESR2ESR1CYP3A4CYP2C9ACMSD | |
| SCHEMBL8732258 | 0.89 | ESR2 (0.33) | ESR2ESR1CYP3A4CYP2C9ACMSD | |
| SCHEMBL8732254 | 0.89 | ESR2 (0.33) | ESR2ESR1CYP3A4CYP2C9ACMSD | |
| SCHEMBL8925406 | 0.85 | ACMSD (0.32) | USP5HDAC6ACMSD | |
| SCHEMBL7765169 | 0.85 | ACMSD (0.32) | USP5HDAC6ACMSD | |
| SCHEMBL8732575 | 0.83 | ESR2 (0.34) | ESR2ESR1CYP3A4CYP2C9ACMSD | |
| SCHEMBL8732580 | 0.83 | ESR2 (0.34) | ESR2ESR1CYP3A4CYP2C9ACMSD | |
| SCHEMBL7767250 | 0.81 | CYP2C9 (0.42) | ESR2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730901-A | Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0742222-A2 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |