Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855116 | 0.84 | EPHX2 (0.50) | MAPK1ALDH1A1TDP1L3MBTL1PDE2A | |
| SCHEMBL425877 | 0.84 | EPHX2 (0.50) | MAPK1ALDH1A1TDP1L3MBTL1PDE2A | |
| SCHEMBL17476838 | 0.82 | AAK1 (0.43) | MAPK1ALDH1A1TDP1L3MBTL1PDE2A | |
| SCHEMBL7807251 | 0.79 | TRPV1 (0.40) | MAPK1ALDH1A1TDP1L3MBTL1PDE2A | |
| SCHEMBL9125985 | 0.77 | PDE2A (0.37) | MAPK1ALDH1A1TDP1PDE2AEPHX2 | |
| SCHEMBL24901470 | 0.77 | USP28 (0.38) | MAPK1L3MBTL1PDE2AEPHX2SLC6A4 | |
| SCHEMBL1044895 | 0.75 | MAPK1 (0.43) | MAPK1ALDH1A1TDP1L3MBTL1SLC6A4 | |
| SCHEMBL7911138 | 0.75 | RECQL (0.42) | MAPK1ALDH1A1TDP1L3MBTL1PDE2A | |
| SCHEMBL27266032 | 0.74 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1SLC6A4 | |
| SCHEMBL9804244 | 0.74 | MAPT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6263678-A | — | — | None | — | — | JP | disclosed |
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |
| JP-H06263678-A | CHLORODIFLUOROMETHOXYPHENYL DERIVATIVE | F HOFFMANN LA ROCHE AG | 1994-09-20 | — | — | JP | disclosed |
| US-4829074-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-09 | — | — | US | disclosed |
| EP-0194064-A2 | Azolyl substituted aralkyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | disclosed |