SCHEMBL4639004

SCHEMBL4639004

Cc1cc(Nc2ccccc2)ccc1-c1ccc(Nc2ccccc2)cc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.58
NPSR1 Q6W5P4 1/20 0.57
ALDH1A1 P00352 8/20 0.56
HSD17B10 Q99714 5/20 0.56
L3MBTL1 Q9Y468 5/20 0.56
TSHR P16473 4/20 0.56
TDP1 Q9NUW8 4/20 0.56
ALOX12 P18054 4/20 0.56
ALOX15 P16050 4/20 0.56
MAPK1 P28482 2/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56
PTGS2 P35354 1/20 0.56
HTR2B P41595 1/20 0.56
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
AR P10275 1/20 0.56
APP P05067 1/20 0.53
CYP3A4 P08684 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13308526 1.00 HPGD (0.58) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL29416259 1.00 HPGD (0.58) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL23567608 0.94 HPGD (0.52) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL20872048 0.87 PLA2G7 (0.50) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL15372181 0.85 PLA2G7 (0.43) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL4826082 0.84 HPGD (0.60) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL30542248 0.84 HPGD (0.60) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL20705368 0.84 ESR2 (0.52) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1
SCHEMBL10755679 0.83 NPSR1 (0.64) HPGDNPSR1ALDH1A1HSD17B10MAPT
SCHEMBL20705367 0.83 ESR2 (0.50) HPGDNPSR1ALDH1A1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3142148-B1 ORGANIC LIGHT EMITTING DISPLAY DEVICE AND LIGHTING APPARATUS FOR VEHICLES USING THE SAME LG DISPLAY CO LTD (KR) 2023-10-18 EP disclosed
US-10177334-B2 Organic light emitting device and display device having the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-08 US disclosed
US-20160276601-A1 ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE HAVING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-22 US disclosed
US-20140299864-A1 POLYMERS CONTAINING THERMALLY DISSOCIABLE AND SOLUBLE GROUPS AND THE USE OF SUCH POLYMERS AS ORGANIC ELECTROLUMINESCENT MATERIALS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-09 US disclosed
US-8795849-B2 Polymers containing thermally dissociable and soluble groups and the use of such polymers as organic electroluminescent materials MITSUBISHI CHEMICAL CORPORATION (JP) 2014-08-05 US disclosed
US-20120193617-A1 LOW-MOLECULAR COMPOUND, POLYMER, ELECTRONIC-DEVICE MATERIAL, COMPOSITION FOR ELECTRONIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC SOLAR CELL ELEMENT, DISPLAY AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-02 US disclosed
US-20110108814-A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-05-12 US disclosed
EP-1885553-A2 BALLISTIC LAMINATE STRUCTURE Composix Co. (US) 2008-02-13 EP disclosed
WO-2006124995-A2 BALLISTIC LAMINATE STRUCTURE COMPOSIX CO. (US) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120193617-A1 LOW-MOLECULAR COMPOUND, POLYMER, ELECTRONIC-DEVICE MATERIAL, COMPOSITION FOR ELECTRONIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC SOLAR CELL ELEMENT, DISPLAY AND LIGHTING EPCAM, CDH1, THEM6 HPGD 4291/4885NPSR1 4141/4885ALDH1A1 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.