Diethyl Phthalate

Diethyl Phthalate

SCHEMBL7765504

C=CC(C)CCCC(C)(C)O.CCOC(=O)c1ccccc1C(=O)OCC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.53
ALDH1A1 P00352 7/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 4/20 0.43
CYP3A4 P08684 3/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 2/20 0.41
CDC25B P30305 1/20 0.41
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Phthalate SCHEMBL28191734 0.78 TSHR (0.53) TSHRALDH1A1HSD17B10KDM4ECYP3A4
Ethyl Anthranilate SCHEMBL4956191 0.75 ALDH1A1 (0.56) TSHRALDH1A1HSD17B10KDM4ECYP3A4
SCHEMBL7809969 0.75 L3MBTL1 (0.42) HSD17B10KDM4ETDP1L3MBTL1MAPK1
Diethyl Phthalate SCHEMBL28329107 0.74 TSHR (0.81) TSHRALDH1A1HSD17B10KDM4ECYP3A4
Diethyl Phthalate SCHEMBL28124298 0.74 TSHR (0.81) TSHRALDH1A1HSD17B10KDM4ECYP3A4
SCHEMBL8338114 0.74 MEN1 (0.41) ALDH1A1CYP3A4
SCHEMBL113015 0.74 MEN1 (0.41) ALDH1A1CYP3A4
SCHEMBL29192 0.74 MEN1 (0.41) ALDH1A1CYP3A4
Alcohol SCHEMBL7209873 0.73 MEN1 (0.38) ALDH1A1CYP3A4
Diethyl Phthalate SCHEMBL27586947 0.72 TSHR (0.91) TSHRALDH1A1HSD17B10KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113782-A1 USE OF MENTHYL-2-PYRROLIDONE-5-CARBOXYLATE AS AN INSECT REPELLENT QUEST INTERNATIONAL B.V. (NL) 2001-07-11 EP disclosed
WO-2000016738-A1 USE OF MENTHYL-2-PYRROLIDONE-5-CARBOXYLATE AS AN INSECT REPELLENT QUEST INTERNATIONAL B.V. (NL) 2000-03-30 WO disclosed