Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.60 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273424 | 0.84 | TRPV4 (0.46) | TRPV4STSRAD51CA1CA2 | |
| SCHEMBL19682467 | 0.81 | TRPV4 (0.49) | TRPV4VCAM1SLC22A12 | |
| SCHEMBL1020883 | 0.81 | TRPV4 (0.60) | TRPV4RAD51CA1CA2HSD11B1 | |
| SCHEMBL29948706 | 0.81 | TRPV4 (0.60) | TRPV4RAD51CA1CA2HSD11B1 | |
| SCHEMBL29948991 | 0.79 | TRPV4 (0.58) | TRPV4RAD51CA1CA2HSD11B1 | |
| SCHEMBL2889391 | 0.79 | TRPV4 (0.63) | TRPV4RAD51CA1CA2HSD11B1 | |
| SCHEMBL2224799 | 0.79 | TRPV4 (0.58) | TRPV4RAD51CA1CA2HSD11B1 | |
| SCHEMBL30033203 | 0.79 | TRPV4 (0.63) | TRPV4RAD51CA1CA2HSD11B1 | |
| SCHEMBL16080223 | 0.79 | TRPV4 (0.46) | TRPV4SLC22A12PTGES2 | |
| SCHEMBL711705 | 0.79 | TRPV4 (0.42) | TRPV4SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945449-B1 | Process for the preparation of saccharincarboxylic acid halides | BASF AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-5981758-A | Preparation of saccharincarbonyl halides | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| EP-0945449-A1 | Process for the preparation of saccharincarboxylic acid halides | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |