Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.54 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383184 | 1.00 | CERT1 (0.67) | CERT1CNR1FAAHLPAR1LPAR3 | |
| SCHEMBL8342096 | 1.00 | CERT1 (0.67) | CERT1CNR1FAAHLPAR1LPAR3 | |
| SCHEMBL7765658 | 1.00 | CERT1 (0.67) | CERT1CNR1FAAHLPAR1LPAR3 | |
| SCHEMBL27623676 | 0.94 | CERT1 (0.59) | CERT1CNR1FAAHLPAR1LPAR3 | |
| SCHEMBL15550810 | 0.93 | CNR1 (0.78) | CERT1CNR1FAAHLPAR1LPAR3 | |
| SCHEMBL15600083 | 0.93 | CNR1 (0.78) | CERT1CNR1FAAHLPAR1LPAR3 | |
| SCHEMBL9069167 | 0.89 | MME (0.60) | CERT1CYP3A4MAPK1 | |
| SCHEMBL13502648 | 0.88 | MAPK1 (0.61) | CERT1CNR1CYP3A4MAPK1 | |
| SCHEMBL9752873 | 0.88 | ITGB3 (0.61) | CERT1FAAHLPAR1LPAR3EPHX2 | |
| SCHEMBL9752875 | 0.88 | ITGB3 (0.61) | CERT1FAAHLPAR1LPAR3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976781-A | DIAGNOSING MALARIA BY MIXING BLOOD WITH ENZYME INHIBITOR, DETERMINING ENZYME ACTIVITY, COMPARING TO CONTROL SAMPLE; PLASMODIUM ENZYME IS MORE SENSITIVE TO INHIBITION SO DEACTIVATION INDICATES DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1999-11-02 | — | — | US | claimed |
| EP-0721446-B1 | CHIRAL SURFACTANTS AND METHODS FOR THEIR USE IN CHIRAL SEPARATIONS | WATERS CORP (US) | 2001-07-18 | — | — | EP | disclosed |