Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.56 |
| ▸ | MME | P08473 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753165 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BFAAHLPAR1LPAR3 | |
| SCHEMBL9753163 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BFAAHLPAR1LPAR3 | |
| SCHEMBL9752873 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BFAAHLPAR1LPAR3 | |
| SCHEMBL9752931 | 0.90 | ENPP2 (0.55) | FAAH | |
| SCHEMBL8383184 | 0.88 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL7765658 | 0.88 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL8342096 | 0.88 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL7765661 | 0.88 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| Phosphonic Acid SCHEMBL9220827 | 0.84 | HPGD (0.58) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL10964933 | 0.83 | CYP1A2 (0.61) | FAAHLPAR1LPAR3EPHX2CERT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | claimed |
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |