Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HK1 | P19367 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596236 | 0.91 | SLC29A1 (0.39) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL6838428 | 0.89 | NSD3 (0.40) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL15532061 | 0.88 | SLC29A1 (0.40) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL7769278 | 0.88 | DHFR (0.41) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL15532145 | 0.87 | SLC29A1 (0.41) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL15532188 | 0.87 | SLC29A1 (0.44) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL15532327 | 0.87 | SLC29A1 (0.37) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL15531950 | 0.86 | CYP1A2 (0.38) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL7765688 | 0.86 | SLC29A1 (0.41) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL7128677 | 0.85 | CYP2C19 (0.41) | SLC29A1CYP1A2CYP2C19CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2846788-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | Akron Molecules AG (AT) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013167743-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | AKRON MOLECULES GMBH (AT) | 2013-11-14 | — | — | WO | disclosed |
| EP-0785208-B1 | Phosphonate nucleotide compounds | MITSUBISHI CHEM CORP (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0785208-A1 | Phosphonate nucleotide compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |