Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838428 | 0.91 | NSD3 (0.40) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL7765668 | 0.91 | SLC29A1 (0.43) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL15532061 | 0.90 | SLC29A1 (0.40) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL15532145 | 0.89 | SLC29A1 (0.41) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL15532188 | 0.89 | SLC29A1 (0.44) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL8094390 | 0.89 | LMNA (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL15532327 | 0.89 | SLC29A1 (0.37) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL15531950 | 0.88 | CYP1A2 (0.38) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL7769278 | 0.84 | DHFR (0.41) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL7898352 | 0.84 | CYP2C19 (0.47) | SLC29A1CYP2C19CYP1A2CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919562-B1 | PHOSPHONATE NUCLEOTIDE COMPOUNDS | MITSUBISHI CHEM CORP (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6194398-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS, HERPES SIMPLEX VIRUS, HEPATITIS B VIRUS; ANTITUMOR AGENTS; SIDE EFFECT REDUCTION; ORAL ABSORPTION BIOAVAILABILITY; A 2-AMINO-6-HYDROCARBYLTHIO-9-(2-(PHOSPHONOMETHOXY)ETHYL-9H-PURINE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0919562-A1 | PHOSPHONATE NUCLEOTIDE COMPOUNDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-02 | — | — | EP | disclosed |