Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283472 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL7763532 | 0.75 | PPID (0.53) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL3781903 | 0.75 | KDM4E (0.54) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL5793295 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL9398072 | 0.74 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL7762785 | 0.73 | HRH3 (0.45) | KDM4EPOLBMAPTLMNAMEN1 | |
| SCHEMBL11431555 | 0.73 | ALDH1A1 (0.71) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL29911395 | 0.73 | ALDH1A1 (0.71) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL9443224 | 0.71 | ALDH1A1 (0.86) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL20702693 | 0.71 | ALDH1A1 (0.81) | ALDH1A1HPGDKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |