Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CHRND | Q07001 | 7/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.48 |
| ▸ | CHRNG | P07510 | 3/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL7764136 | 0.95 | TLR2 (0.50) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7762775 | 0.93 | CPB2 (0.49) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7758999 | 0.91 | CALCRL (0.54) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Aniline SCHEMBL7762808 | 0.89 | CPB2 (0.46) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7759027 | 0.88 | CPB2 (0.50) | CPB2GNPAT | |
| SCHEMBL7761873 | 0.87 | GNPAT (0.52) | CPB2CPB1GNPAT | |
| Aniline SCHEMBL7762780 | 0.87 | CALCRL (0.52) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7765746 | 0.85 | NTMT1 (0.48) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL7763474 | 0.85 | NTMT1 (0.48) | TLR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7759040 | 0.84 | CPB2 (0.46) | CPB2GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |