Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | SI | P14410 | 6/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822007 | 0.95 | MGAM (0.59) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL7759238 | 0.85 | MGAM (0.51) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL7763616 | 0.85 | ACHE (0.64) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL7820409 | 0.84 | AURKA (0.67) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL3577220 | 0.83 | AURKA (0.71) | AURKAPARP1AURKB | |
| SCHEMBL7762915 | 0.82 | MGAM (0.55) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL7761994 | 0.82 | CYP1A2 (0.52) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL7763627 | 0.81 | GAA (0.51) | MGAMGAASIMGAM2AURKA | |
| SCHEMBL6584337 | 0.80 | AURKB (0.53) | AURKAPARP1KCNH2AURKBHPSE | |
| SCHEMBL7764169 | 0.80 | MGAM (0.52) | MGAMGAASIMGAM2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
| EP-1127052-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026192-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |