Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | GNRHR | P30968 | 5/20 | 0.47 |
| ▸ | MGAM | O43451 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | SI | P14410 | 5/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763616 | 0.90 | ACHE (0.64) | AURKAAURKBACHEGNRHRMGAM | |
| SCHEMBL3582845 | 0.85 | AURKB (0.93) | AURKAAURKBPARP1 | |
| SCHEMBL7765849 | 0.84 | MGAM (0.54) | AURKAAURKBACHEMGAMGAA | |
| SCHEMBL7761994 | 0.84 | CYP1A2 (0.52) | AURKAAURKBACHEDRD2DRD3 | |
| SCHEMBL7763605 | 0.83 | AURKA (0.47) | AURKAAURKBDRD2DRD3GNRHR | |
| SCHEMBL6583299 | 0.83 | AURKB (0.71) | AURKAAURKBACHEDRD2DRD3 | |
| SCHEMBL7822007 | 0.81 | MGAM (0.59) | AURKAAURKBACHEMGAMGAA | |
| SCHEMBL3574435 | 0.80 | AURKB (1.00) | AURKAAURKBPARP1 | |
| SCHEMBL7759238 | 0.79 | MGAM (0.51) | AURKAAURKBACHEMGAMGAA | |
| SCHEMBL7819660 | 0.79 | AURKB (0.71) | AURKAAURKBACHEDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127052-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026192-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |