Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 13/20 | 0.51 |
| ▸ | GAA | P10253 | 13/20 | 0.51 |
| ▸ | SI | P14410 | 13/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 13/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763628 | 0.91 | MGAM (0.53) | MGAMGAASIMGAM2MMP2 | |
| SCHEMBL3584741 | 0.75 | PARP1 (0.59) | — | |
| SCHEMBL6579004 | 0.73 | PARP1 (0.41) | — | |
| SCHEMBL7854331 | 0.69 | MGAM (0.58) | MGAMGAASIMGAM2MMP2 | |
| SCHEMBL5074029 | 0.69 | MGAM (0.76) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL30615069 | 0.69 | MGAM (0.76) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL7047918 | 0.69 | MGAM (0.68) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL6325053 | 0.68 | GAA (0.72) | MGAMGAASIMGAM2HPSE | |
| SCHEMBL3577208 | 0.67 | PARP1 (0.55) | — | |
| SCHEMBL1170892 | 0.67 | MGAM (0.71) | MGAMGAASIMGAM2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |