Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010056 | 0.90 | POLB (1.00) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2913783 | 0.86 | POLB (0.61) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL19448886 | 0.84 | PKM (0.68) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17509872 | 0.84 | POLB (0.59) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9345619 | 0.84 | POLB (0.59) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12531500 | 0.84 | HPGD (0.68) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13662282 | 0.83 | POLB (0.79) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4385068 | 0.83 | POLB (0.57) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL593172 | 0.82 | MAPT (0.74) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8533501 | 0.81 | POLB (0.76) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617005-B1 | Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same | FUJI XEROX CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-5587263-A | STABLE CHARGE TRANSPORT LAYER | FUJI XEROX CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5495049-A | CHARGE TRANSFER COMPOUNDS | FUJI XEROX CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0617005-A2 | Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same | FUJI XEROX CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-4699651-A | Use of certain cinnoline-4-carboxylic acids and congeners thereof for controlling the growth of unwanted plants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| US-4666499-A | Herbicidal 2 methyl-4-phosphinylcinnolinium hydroxide inner salts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0212726-A2 | Herbicidal cinnoline compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-03-04 | — | — | EP | disclosed |
| US-4620000-A | Method for preparing 4-hydroxycinnolines in a pH controlled system | SHELL OIL COMPANY (US) | 1986-10-28 | — | — | US | disclosed |