⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773591 | 0.82 | GAA (0.39) | — | |
| SCHEMBL7771359 | 0.80 | EPHX1 (0.36) | — | |
| SCHEMBL7765955 | 0.80 | — | — | |
| SCHEMBL12707280 | 0.79 | GAA (0.35) | — | |
| SCHEMBL7771471 | 0.78 | KDM4E (0.38) | — | |
| SCHEMBL7765897 | 0.77 | HTT (0.39) | — | |
| SCHEMBL7770065 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL7773641 | 0.76 | EPHX1 (0.46) | — | |
| SCHEMBL7769422 | 0.74 | EPHX1 (0.33) | — | |
| SCHEMBL7771576 | 0.72 | TDP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |