SCHEMBL7765897

SCHEMBL7765897

CC(C)(NC(=O)OCC(F)(F)F)C([NH])=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765906 0.81 HTT (0.39) HTTCNR2
SCHEMBL9547614 0.80 HTT (0.45) HTTCNR2
SCHEMBL7773591 0.79 GAA (0.39) HTT
SCHEMBL7765949 0.77
SCHEMBL7771471 0.76 KDM4E (0.38)
SCHEMBL7770065 0.73 ALDH1A1 (0.30)
SCHEMBL7773641 0.73 EPHX1 (0.46)
SCHEMBL7769422 0.71 EPHX1 (0.33)
SCHEMBL965595 0.71 HTT (0.48) HTT
SCHEMBL21680782 0.71 HTT (0.43) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed