Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.55 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803971 | 0.83 | ESR1 (0.32) | HRH3LOXL2 | |
| SCHEMBL15828 | 0.83 | HRH3 (0.79) | HRH3LOXL2ABATTAAR1CA1 | |
| SCHEMBL232738 | 0.81 | — | — | |
| Formaldehyde SCHEMBL28778127 | 0.80 | HRH3 (0.65) | HRH3LOXL2ABATTAAR1CA1 | |
| Hydrochloric Acid SCHEMBL3168189 | 0.79 | HRH3 (0.73) | HRH3LOXL2ABATTAAR1CA1 | |
| Iodide SCHEMBL29191162 | 0.79 | HRH3 (0.73) | HRH3LOXL2ABATTAAR1CA1 | |
| Hydrochloric Acid SCHEMBL3162690 | 0.79 | HRH3 (0.73) | HRH3LOXL2ABATTAAR1CA1 | |
| Bromide SCHEMBL29198706 | 0.79 | HRH3 (0.73) | HRH3LOXL2ABATTAAR1CA1 | |
| Iodide SCHEMBL28395414 | 0.79 | HRH3 (0.73) | HRH3LOXL2ABATTAAR1CA1 | |
| SCHEMBL23201127 | 0.78 | LOXL2 (0.55) | HRH3LOXL2TAAR1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504155-B1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | ROCHE DIAGNOSTICS GMBH (DE) | 2023-03-08 | — | — | EP | claimed |
| US-20220169664-A1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESS FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2022-06-02 | — | — | US | claimed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | claimed |
| CN-110139828-B | Multifunctional silicon nanoparticles, method for the production thereof and use thereof in electrochemiluminescence-based detection methods | 豪夫迈·罗氏有限公司 | 2021-05-28 | — | — | CN | claimed |
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | claimed |
| CN-110392680-A | Substituted azolyl pyrrolidones and azolyl hydantoins and salts thereof and their use as herbicidal active substances | 拜耳作物科学股份公司 | 2019-10-29 | — | — | CN | claimed |
| CN-110139828-A | Multifunctional silicon nanoparticles, method for the production thereof and use thereof in electrochemiluminescence-based detection methods | 豪夫迈·罗氏有限公司 | 2019-08-16 | — | — | CN | claimed |
| EP-3504155-A1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | Roche Diagnostics GmbH (DE) | 2019-07-03 | — | — | EP | claimed |
| WO-2018037060-A1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | ROCHE DIAGNOSTICS GMBH (DE) | 2018-03-01 | — | — | WO | claimed |
| CN-102250458-B | Poly carbonate resin composition and moulded product thereof | CHEIL INDUSTRIES INC. (KR) | 2016-01-27 | — | — | CN | claimed |
| CN-101798450-A | Polylactic acid/polycarbonate resin composition and molded product made using the same | CHEIL IND INC | 2010-08-11 | — | — | CN | claimed |
| CN-101410366-A | Substituted bicyclic ring derivatives and uses thereof | ASAHI KASEI PHARMA CORP (JP) | 2009-04-15 | — | — | CN | claimed |
| CN-100364973-C | Indolone-acetamide derivatives, processes for preparing them and their uses | UCB SA (BE) | 2008-01-30 | — | — | CN | claimed |
| CN-1768036-A | Indolone-acetamide derivatives, processes for preparing them and their uses | UCB SA (BE) | 2006-05-03 | — | — | CN | claimed |
| CN-1231465-C | Biphenylsulfonyl cyanamides, method for the production thereof and use thereof as medicaments | AVENTIS PHARMACEUTIC DEUTSCHLA (DE) | 2005-12-14 | — | — | CN | claimed |
| EP-0759457-B1 | Weather and soiling-resistant silicone-containing coating composition | SHINETSU CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | claimed |
| CN-1224426-A | 3-descladinose-2, 3-anhydroerythromycin derivatives | ABBOTT LAB (US) | 1999-07-28 | — | — | CN | claimed |
| US-5814703-A | ORGANIC RESIN AND SILICONE COMPOUND; PROTECTIVE COATINGS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-09-29 | — | — | US | claimed |
| EP-0759457-A2 | Weather and soiling-resistant silicone-containing coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-02-26 | — | — | EP | claimed |
| CN-1119014-A | Benzopyranes as potassium channel openers | PFIZER LTD (GB) | 1996-03-20 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169664-A1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESS FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | SELE, SIK1, SIK2 | HRH3 4691/4885LOXL2 1652/4885ABAT 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.