SCHEMBL7766008

SCHEMBL7766008

Fc1cccc(OCCI)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
GRM2 Q14416 2/20 0.40
HTR1A P08908 1/20 0.39
KDM4E B2RXH2 3/20 0.38
FFAR1 O14842 1/20 0.36
MEN1 O00255 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
KMT2A Q03164 2/20 0.36
RECQL P46063 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
TRPA1 O75762 1/20 0.36
HTR1B P28222 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23112144 0.82 KDM4E (0.59) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL27695068 0.82 KDM4E (0.43) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL28622975 0.82 HTR2A (0.44) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL1007504 0.80 GRM2 (0.43) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL4170381 0.80 L3MBTL1 (0.42) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL30750877 0.80 SLC6A2 (0.44) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL17393516 0.80 SLC6A2 (0.44) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL6479626 0.80 L3MBTL1 (0.42) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL8216509 0.80 L3MBTL1 (0.50) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL5706786 0.80 GRM2 (0.42) L3MBTL1TDP1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668285-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 2001-05-02 EP disclosed
US-5543539-A TRANS CONFIGURATION DISPLAY ELEMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-06 US disclosed