⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135565 | 0.79 | — | — | |
| SCHEMBL18980132 | 0.79 | — | — | |
| SCHEMBL11997982 | 0.79 | — | — | |
| SCHEMBL25663961 | 0.77 | CA1 (0.39) | — | |
| SCHEMBL25663960 | 0.77 | CA1 (0.39) | — | |
| SCHEMBL27702123 | 0.77 | — | — | |
| SCHEMBL26343506 | 0.77 | L3MBTL1 (0.33) | — | |
| SCHEMBL859838 | 0.77 | CHRM1 (0.36) | — | |
| SCHEMBL12301657 | 0.77 | KCNH2 (0.31) | — | |
| SCHEMBL1432394 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3674096-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PLATE FABRICATION METHOD | FUJIFILM Corporation (JP) | 2020-07-01 | — | — | EP | disclosed |
| US-8501693-B2 | Use of exendins and exendin agonists and GLP-1 receptor agonists for altering the concentration of fibrinogen | AMYLIN PHARMACEUTICALS, LLC (US) | 2013-08-06 | — | — | US | disclosed |
| US-20130023470-A1 | EXENDIN AND EXENDIN AGONISTS FOR EATING DISORDERS | AMYLIN PHARMACEUTICALS, LLC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-20100144621-A1 | Use of Exendins and Exendin Agonists and GLP-1 Receptor Agonists for Altering the Concentration of Fibrinogen | AMYLIN PHARMACEUTICALS, INC. | 2010-06-10 | — | — | US | disclosed |
| US-20090209469-A1 | Use of Exendins and GLP-1 Receptor Agonists for Altering Lipoprotein Particle Size and Subclass Composition | ELI LILLY AND COMPANY | 2009-08-20 | — | — | US | disclosed |
| US-20080125353-A1 | Use of Exendins and Agonists Thereof for the Treatment of Gestational Diabetes Mellitus | ASTRAZENECA PHARMACEUTICALS LP | 2008-05-29 | — | — | US | disclosed |
| US-7223725-B1 | Exendin agonist compounds | AMYLIN PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-6506724-B1 | Exendins are peptides that were first isolated from the salivary secretions of the Gila-monster, a lizard found in Arizona and have some sequence similarity to several members of the glucagon-like peptide | AMYLIN PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |