Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766081 | 1.00 | MMP13 (0.32) | MMP13MMP14ITGB3ITGA2BHTT | |
| SCHEMBL7767647 | 0.90 | ITGB3 (0.34) | ITGB3ITGA2BALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7767644 | 0.90 | ITGB3 (0.34) | ITGB3ITGA2BALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7767642 | 0.90 | ITGB3 (0.34) | ITGB3ITGA2BALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7765414 | 0.88 | ITGB3 (0.33) | MMP13MMP14ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7765401 | 0.88 | ITGB3 (0.33) | MMP13MMP14ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7765408 | 0.88 | ITGB3 (0.33) | MMP13MMP14ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7767246 | 0.87 | ITGB3 (0.33) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7767243 | 0.87 | ITGB3 (0.33) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7767242 | 0.87 | ITGB3 (0.33) | ITGB3ITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |