Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20872654 | 0.79 | HTR2C (0.46) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL29628543 | 0.79 | HTR2C (0.46) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL15740410 | 0.78 | SMN1; SMN2 (0.42) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL30236658 | 0.78 | SMN1; SMN2 (0.42) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL29451144 | 0.77 | PIK3CD (0.39) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL21930097 | 0.77 | SMN1; SMN2 (0.41) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL5972769 | 0.77 | MAPT (0.47) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL20704973 | 0.77 | PIK3CD (0.39) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL8232189 | 0.76 | ALDH1A1 (0.46) | S1PR4SMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL16555251 | 0.76 | SLC6A4 (0.49) | S1PR4SMN1; SMN2NPC1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |