Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760598 | 1.00 | TSHR (0.51) | TSHRKCNMA1CDK2TDP1L3MBTL1 | |
| SCHEMBL30063181 | 0.88 | ATR (0.52) | TSHRKCNMA1TDP1L3MBTL1MAPT | |
| SCHEMBL1421011 | 0.88 | ATR (0.52) | TSHRKCNMA1TDP1L3MBTL1MAPT | |
| SCHEMBL8651106 | 0.84 | ATR (0.47) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3874517 | 0.84 | ALDH1A1 (0.51) | TSHRKCNMA1L3MBTL1MAPTMEN1 | |
| SCHEMBL28607387 | 0.84 | KCNMA1 (0.55) | TSHRKCNMA1TDP1L3MBTL1MAPT | |
| SCHEMBL6929852 | 0.84 | KCNMA1 (0.49) | KCNMA1TDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL4591743 | 0.83 | MAPT (0.42) | KCNMA1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27835430 | 0.83 | MAPT (0.44) | KCNMA1TDP1MAPTMEN1KMT2A | |
| Benzoic Acid SCHEMBL8866912 | 0.83 | ALDH1A1 (0.50) | TSHRKCNMA1L3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929597-B | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2025-02-18 | — | — | CN | claimed |
| EP-0881212-B1 | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-31 | — | — | EP | claimed |
| CN-113929597-B | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113929597-B | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113544113-B | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116730871-A | Synthesis method of candesartan intermediate | 湖北郡泰医药化工有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116410189-A | Pyrimido pyridine compound and medicinal composition and application thereof | 中国科学院上海药物研究所 | 2023-07-11 | — | — | CN | disclosed |
| EP-3083582-A1 | A NEW PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL | Farma GRS, d.o.o. (SI) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015090635-A1 | A NEW PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL | FARMA GRS, D.O.O. (SI) | 2015-06-25 | — | — | WO | disclosed |
| EP-0591026-A1 | Piperidine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1994-04-06 | — | — | EP | disclosed |