Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850867 | 0.91 | ABL1 (0.47) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL7454751 | 0.89 | NPC1 (0.57) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL31260432 | 0.89 | NPC1 (0.57) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL15249622 | 0.89 | SMN1; SMN2 (0.58) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL12257971 | 0.89 | SMN1; SMN2 (0.58) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL3392425 | 0.85 | KDM4E (0.53) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL12655918 | 0.84 | ACACA (0.52) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL32685182 | 0.84 | TGFBR1 (0.54) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL3392131 | 0.84 | KDM4E (0.51) | NPC1RAB9AHSP90AA1L3MBTL1PKM | |
| SCHEMBL31187066 | 0.83 | NPC1 (0.51) | NPC1RAB9AHSP90AA1L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |