Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573447 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL29637876 | 0.73 | MPO (0.38) | HDAC8 | |
| SCHEMBL29637877 | 0.71 | FABP3 (0.38) | HDAC8 | |
| SCHEMBL29614893 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL6014064 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL1009054 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL29150788 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL14989322 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL11794173 | 0.66 | HDAC6 (0.43) | HDAC8 | |
| SCHEMBL573494 | 0.63 | PRNP (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092273-A2 | BENZENEDICARBOXYLIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |