Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011939 | 0.82 | NPC1 (0.37) | TDP1NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL30967742 | 0.82 | NPC1 (0.37) | TDP1NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL7731859 | 0.78 | CTDSP1 (0.45) | NPC1RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL9647393 | 0.72 | MAPT (0.52) | TDP1NPC1RAB9AKDM4ETP53 | |
| SCHEMBL30967743 | 0.71 | GRIK1 (0.43) | SMN1; SMN2ALDH1A1KMT2AACP1CASR | |
| SCHEMBL30967744 | 0.71 | GRIK1 (0.43) | SMN1; SMN2ALDH1A1KMT2AACP1CASR | |
| SCHEMBL11151982 | 0.70 | ACP1 (0.35) | ALDH1A1KMT2AACP1PTPN12CASR | |
| SCHEMBL12830031 | 0.70 | CNR2 (0.42) | KDM4ESMN1; SMN2ALDH1A1KMT2ACA1 | |
| SCHEMBL12829324 | 0.70 | ALDH1A1 (0.47) | TP53ALDH1A1KMT2AACP1CASR | |
| SCHEMBL9647340 | 0.70 | DDX3X (0.57) | TDP1NPC1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803543-B1 | Fiber-reactive dyes, preparation and use thereof | CIBA SC HOLDING AG (CH) | 2001-03-07 | — | — | EP | disclosed |
| EP-0812886-B1 | Reactive dyestuffs, their preparation and use thereof | CIBA SC HOLDING AG (CH) | 2001-02-21 | — | — | EP | disclosed |
| EP-0812886-A1 | Reactive dyestuffs, their preparation and use thereof | Ciba SC Holding AG (CH) | 1997-12-17 | — | — | EP | disclosed |
| EP-0803543-A1 | Fiber-reactive dyes, preparation and use thereof | Ciba SC Holding AG (CH) | 1997-10-29 | — | — | EP | disclosed |