SCHEMBL7766757

SCHEMBL7766757

CCCC(OC(=O)CC(=O)OCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C1CC(C)(C)N(C)C(C)(C)C1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.36
HTT P42858 2/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 7/20 0.32
KDM4E B2RXH2 4/20 0.32
MAPT P10636 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
ALOX15 P16050 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1695268 0.83 GAA (0.37) GAAHTTPKMKMT2AALDH1A1
SCHEMBL22260995 0.82 GAA (0.36) GAAHTTPKMKMT2AALDH1A1
SCHEMBL1695272 0.81 GAA (0.36) GAAHTTPKMKMT2AALDH1A1
SCHEMBL7212084 0.78 GAA (0.37) GAAHTTPKMKMT2AALDH1A1
SCHEMBL22260997 0.77 GAA (0.34) GAAHTTPKMKMT2AALDH1A1
SCHEMBL28473328 0.77 GAA (0.36) GAAHTTPKMKMT2AALDH1A1
SCHEMBL21822067 0.76 GAA (0.37) GAAHTTPKMKMT2AALDH1A1
SCHEMBL29612236 0.76 GAA (0.34) GAAHTTPKMKMT2AALDH1A1
SCHEMBL2319233 0.76 NR5A2 (0.35) GAAHTTPKMALDH1A1KDM4E
SCHEMBL3836055 0.75 GAA (0.37) GAAHTTPKMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
EP-1110999-A2 Stabilizing mixtures for organic polymers Great Lakes Chemical (Europe) GmbH (CH) 2001-06-27 EP disclosed
US-5283273-A With sterically hindered amine; zinc, calcium, magnesium and/or barium compound; a 1,3-dicarbonyl compound: no organotin or hydrotalcite compounds and no blowing or foaming agents CIBA-GEIGY CORPORATION (US) 1994-02-01 US disclosed
US-5198130-A Zinc thiophosphates, tetramethylpiperidine derivatives CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M GAA 3145/4885HTT 634/4885PKM 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.