Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764862 | 0.79 | EHMT2 (0.47) | EHMT2TSHRCYP3A4CYP2C19MMP1 | |
| SCHEMBL9381553 | 0.72 | EHMT2 (0.38) | EHMT2TSHRCYP3A4CYP2C19RXFP1 | |
| SCHEMBL7762226 | 0.70 | CRBN (0.40) | EHMT2TSHRCYP3A4CYP2C19RXFP1 | |
| SCHEMBL7765779 | 0.70 | CRBN (0.40) | EHMT2TSHRCYP3A4CYP2C19RXFP1 | |
| SCHEMBL7764867 | 0.66 | MEN1 (0.40) | EHMT2MMP1MMP9ALDH1A1MEN1 | |
| SCHEMBL7769377 | 0.66 | CRBN (0.39) | EHMT2TSHRCYP3A4CYP2C19MMP1 | |
| SCHEMBL30748807 | 0.66 | HCRTR1 (0.47) | EHMT2TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL30749017 | 0.66 | HCRTR1 (0.47) | EHMT2TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL10696574 | 0.65 | TSHR (0.51) | EHMT2TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL17426060 | 0.64 | EHMT2 (0.51) | EHMT2TSHRCYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |