SCHEMBL7766926

SCHEMBL7766926

CCCCCCOc1ccc(-c2ccc(C(=O)Cl)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.75
TP53 P04637 1/20 0.67
TSHR P16473 1/20 0.67
PLA2G4B P0C869 6/20 0.65
PLA2G4A P47712 1/20 0.58
THRA P10827 2/20 0.56
THRB P10828 2/20 0.56
GAA P10253 1/20 0.56
NR5A1 Q13285 1/20 0.56
PTPN11 Q06124 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502541 1.00 RARB (0.75) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL9274539 1.00 RARB (0.75) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL7767495 1.00 RARB (0.75) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL7766930 1.00 RARB (0.75) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL7768450 1.00 RARB (0.75) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL641552 1.00 RARB (0.75) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL9450551 0.98 RARB (0.72) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8728342 0.95 TP53 (0.73) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL4209056 0.95 TP53 (0.73) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL9161795 0.95 TP53 (0.73) RARBTP53TSHRPLA2G4BPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684246-B1 Optically active tetrahydropyran derivative, liquid crystal composition, and liquid crystal device containing the same KASHIMA OIL (JP) 2001-10-17 EP disclosed
US-6096908-A TETRAHYDRO-2-ACETOXY-6-TRIFLUOROMETHYL-5-HYDROXYPYRAN OPTICAL ISOMERS KASHIMA OIL COMPANY (JP) 2000-08-01 US disclosed
EP-0741136-B1 Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative KASHIMA OIL (JP) 1999-09-08 EP disclosed
US-5811028-A Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative KASHIMA OIL COMPANY (JP) 1998-09-22 US disclosed
EP-0594861-B1 OPTICALLY ACTIVE TETRAHYDROPYRAN DERIVATIVE, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT BOTH CONTAINING THE SAME KASHIMA OIL (JP) 1998-03-18 EP disclosed
US-5705093-A LIQUID CRYSTAL MEDIA WITH OPTICAL ACTIVITY FOR DECORATIONS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-01-06 US disclosed
US-5698137-A Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative KASHIMA OIL COMPANY (JP) 1997-12-16 US disclosed
EP-0622441-B1 Ferroelectric liquid crystal mixture and liquid crystal device using the same SHARP KK (JP) 1997-11-19 EP disclosed
US-5595684-A TETRAHYDROPYRAN DERIVATIVES OF SILANOL WITH FLUOROALKYL GROUPS FOR FERROELECTRIC LIQUID CRYSTALS WITH SPONTANEOUS POLARIZATION KASHIMA OIL COMPANY (JP) 1997-01-21 US disclosed
EP-0741136-A1 Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative KASHIMA OIL COMPANY (JP) 1996-11-06 EP disclosed
EP-0684246-A1 Optically active tetrahydropyran derivative, liquid crystal composition, and liquid crystal device containing the same KASHIMA OIL COMPANY (JP) 1995-11-29 EP disclosed
US-5443755-A Optically active tetrahydropyrane derivatives, liquid crystal composition and liquid crystal device containing the same KASHIMA OIL COMPANY (JP) 1995-08-22 US disclosed
US-5437814-A Having fluorine-containing pyranyl group SHARP KABUSHIKI KAISHA (JP) 1995-08-01 US disclosed
US-5368771-A Enantiomorphs KASHIMA OIL COMPANY (JP) 1994-11-29 US disclosed
EP-0622441-A1 Ferroelectric liquid crystal mixture and liquid crystal device using the same SHARP KABUSHIKI KAISHA (JP) 1994-11-02 EP disclosed
EP-0594861-A1 OPTICALLY ACTIVE TETRAHYDROPYRAN DERIVATIVE, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT BOTH CONTAINING THE SAME KASHIMA OIL COMPANY (JP) 1994-05-04 EP disclosed