Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.65 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502541 | 1.00 | RARB (0.75) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9274539 | 1.00 | RARB (0.75) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7766926 | 1.00 | RARB (0.75) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7766930 | 1.00 | RARB (0.75) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7768450 | 1.00 | RARB (0.75) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL641552 | 1.00 | RARB (0.75) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9450551 | 0.98 | RARB (0.72) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL8728342 | 0.95 | TP53 (0.73) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL4209056 | 0.95 | TP53 (0.73) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9161795 | 0.95 | TP53 (0.73) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684246-B1 | Optically active tetrahydropyran derivative, liquid crystal composition, and liquid crystal device containing the same | KASHIMA OIL (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5595684-A | TETRAHYDROPYRAN DERIVATIVES OF SILANOL WITH FLUOROALKYL GROUPS FOR FERROELECTRIC LIQUID CRYSTALS WITH SPONTANEOUS POLARIZATION | KASHIMA OIL COMPANY (JP) | 1997-01-21 | — | — | US | disclosed |