Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 17/20 | 0.69 |
| ▸ | KCNQ1 | P51787 | 17/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767221 | 1.00 | KCNE1 (0.69) | KCNE1KCNQ1KCNH2MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11611527 | 0.85 | KCNE1 (0.48) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11611521 | 0.85 | KCNE1 (0.48) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11611531 | 0.85 | KCNE1 (0.48) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6934962 | 0.83 | KCNE1 (0.75) | KCNE1KCNQ1KCNH2MEN1CYP1A2 | |
| SCHEMBL7763690 | 0.81 | KCNE1 (0.73) | KCNE1KCNQ1KCNH2MEN1CYP1A2 | |
| SCHEMBL7763684 | 0.81 | KCNE1 (0.73) | KCNE1KCNQ1KCNH2MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11611577 | 0.80 | KCNE1 (0.46) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11611574 | 0.80 | KCNE1 (0.46) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9397665 | 0.80 | KDM4E (0.64) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109801-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014084-A1 | SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |