Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830906 | 0.94 | KMT2A (0.50) | ESR2KMT2AMEN1CA12CA1 | |
| SCHEMBL8779173 | 0.92 | KMT2A (0.52) | ESR2KMT2AMEN1ELANEHSD17B10 | |
| SCHEMBL29044797 | 0.87 | ESR2 (0.54) | ESR2ABL1ABCB1BCRKMT2A | |
| SCHEMBL8059094 | 0.87 | ESR2 (0.54) | ESR2ABL1ABCB1BCRKMT2A | |
| SCHEMBL676909 | 0.85 | KMT2A (0.58) | KMT2AMEN1CA1CA2ELANE | |
| SCHEMBL2058536 | 0.84 | GAA (0.55) | KMT2AMEN1HSD17B10MAPTNPC1 | |
| SCHEMBL14205190 | 0.84 | LMNA (0.55) | KMT2AMEN1HSD17B10MAPTNPC1 | |
| SCHEMBL16429581 | 0.83 | CA1 (0.60) | ESR2KMT2AMEN1CA12CA1 | |
| SCHEMBL16429580 | 0.83 | CA1 (0.60) | ESR2KMT2AMEN1CA12CA1 | |
| SCHEMBL6228012 | 0.82 | SLC6A3 (0.47) | KMT2AMEN1HSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002540-A1 | FOAMED POLYURETHANE COMPOSITIONS | PRESIDIUM INNOVATIONS, LLC | 2023-01-05 | — | — | US | disclosed |
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |