Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766976 | 1.00 | KDM1A (0.34) | KDM1ADRD2DRD3TNK2CNR2 | |
| SCHEMBL7766981 | 1.00 | KDM1A (0.34) | KDM1ADRD2DRD3TNK2CNR2 | |
| SCHEMBL7767782 | 0.91 | KDM1A (0.43) | KDM1A | |
| SCHEMBL7767779 | 0.91 | KDM1A (0.43) | KDM1A | |
| SCHEMBL7767784 | 0.91 | KDM1A (0.43) | KDM1A | |
| SCHEMBL8417308 | 0.85 | PDE2A (0.34) | KDM1A | |
| SCHEMBL8417305 | 0.85 | PDE2A (0.34) | KDM1A | |
| SCHEMBL7769893 | 0.85 | CACNA1G (0.37) | DRD2DRD3 | |
| SCHEMBL7762536 | 0.85 | KDM1A (0.37) | KDM1ADRD2DRD3CNR2 | |
| SCHEMBL7769899 | 0.85 | CACNA1G (0.37) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |