Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417305 | 1.00 | PDE2A (0.34) | PDE2AEPHX2KDM1ACYP2C9SLC7A5 | |
| SCHEMBL8005232 | 0.92 | CTSK (0.34) | PDE2AEPHX2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8005234 | 0.92 | CTSK (0.34) | PDE2AEPHX2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8005238 | 0.92 | CTSK (0.34) | PDE2AEPHX2CYP2C9ALDH1A1LMNA | |
| SCHEMBL9008499 | 0.92 | CTSK (0.34) | PDE2AEPHX2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8015318 | 0.91 | EPHX2 (0.32) | PDE2AEPHX2 | |
| SCHEMBL8015320 | 0.91 | EPHX2 (0.32) | PDE2AEPHX2 | |
| SCHEMBL9008525 | 0.91 | EPHX2 (0.32) | PDE2AEPHX2 | |
| SCHEMBL8015315 | 0.91 | EPHX2 (0.32) | PDE2AEPHX2 | |
| SCHEMBL7769939 | 0.91 | EPHX2 (0.33) | PDE2AEPHX2KDM1ACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |