Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.81 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.81 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.81 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.74 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.70 |
| ▸ | GSK3B | P49841 | 2/20 | 0.68 |
| ▸ | BACE1 | P56817 | 2/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.65 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 3/20 | 0.60 |
| ▸ | RXRB | P28702 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059143 | 0.90 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL228477 | 0.90 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL6830467 | 0.90 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL11603274 | 0.89 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL11273693 | 0.89 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL11603952 | 0.89 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| Hydrochloric Acid SCHEMBL8544438 | 0.89 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL14786203 | 0.87 | LCK (0.77) | GSK3BBACE1ABCG2MAOBLCK | |
| SCHEMBL20024692 | 0.87 | LCK (0.77) | GSK3BBACE1ABCG2MAOBLCK | |
| SCHEMBL1221359 | 0.85 | NR4A2 (0.90) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| CN-1150589-A | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1997-05-28 | — | — | CN | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |