Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17877588 | 0.78 | MRGPRX4 (0.38) | ALDH1A1MAPK1SLC6A4LMNARAB9A | |
| SCHEMBL2091964 | 0.77 | DGAT1 (0.40) | DGAT1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL19723801 | 0.77 | ALDH1A1 (0.39) | DGAT1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL8994745 | 0.76 | AKR1B1 (0.33) | AAK1KDM1AKDM1B | |
| SCHEMBL7766222 | 0.75 | MAPT (0.33) | MAPK1MAPTHTTKMT2A | |
| SCHEMBL27266032 | 0.73 | MAPK1 (0.58) | DGAT1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL7766219 | 0.72 | DGAT1 (0.39) | DGAT1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL5540402 | 0.71 | SLC6A4 (0.42) | DGAT1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL13672840 | 0.70 | DGAT1 (0.44) | DGAT1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL282059 | 0.70 | HTT (0.50) | ALDH1A1L3MBTL1MAPK1TDP1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |