Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3252060 | 0.82 | LMNA (0.85) | LMNAMTNR1AMTNR1BALOX15ADRB2 | |
| SCHEMBL2943775 | 0.82 | LMNA (1.00) | LMNAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL50453 | 0.82 | LMNA (1.00) | LMNAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL3254859 | 0.82 | LMNA (1.00) | LMNAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL1618880 | 0.82 | LMNA (1.00) | LMNAALDH1A1KDM4EMTNR1AMTNR1B | |
| Benzoic Acid SCHEMBL7771041 | 0.81 | LMNA (0.76) | LMNAHPGDNAPRTMTNR1AMTNR1B | |
| Salicylic Acid SCHEMBL4194185 | 0.80 | ALDH1A1 (0.67) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL15568422 | 0.80 | ALDH1A1 (0.78) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL27871001 | 0.80 | ALDH1A1 (0.78) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL28403214 | 0.80 | ALDH1A1 (0.60) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763579-B1 | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | HEWLETT PACKARD CO (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0839881-A2 | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | Hewlett-Packard Company (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5713989-A | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | HEWLETT-PACKARD COMPANY (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0763579-A1 | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | Hewlett-Packard Company (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5531816-A | Bleed-alleviated, waterfast, pigment-based ink-jet ink compositions | HEWLETT-PACKARD COMPANY (US) | 1996-07-02 | — | — | US | disclosed |