Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.71 |
| ▸ | DRD3 | P35462 | 14/20 | 0.71 |
| ▸ | DRD4 | P21917 | 6/20 | 0.71 |
| ▸ | HTR1A | P08908 | 3/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | HTR2C | P28335 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7766162 | 0.99 | DRD2 (0.70) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769974 | 0.91 | DRD2 (0.76) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769531 | 0.91 | DRD2 (0.79) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7766165 | 0.90 | DRD2 (0.75) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7767904 | 0.90 | DRD2 (0.77) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7767949 | 0.90 | DRD2 (0.77) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7767185 | 0.85 | DRD2 (0.84) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7762559 | 0.84 | DRD2 (0.82) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769911 | 0.84 | DRD2 (0.90) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7766194 | 0.83 | DRD2 (0.76) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873329-B1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2001-06-06 | — | — | EP | claimed |