Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL29279195 | 0.89 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2CYP2C19CYP2C9 | |
| SCHEMBL506307 | 0.83 | MTOR (0.54) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2054822 | 0.83 | EPHX2 (0.50) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1094537 | 0.82 | CNR1 (0.57) | SMN1; SMN2CYP2C19RAB9ACYP1A2NPC1 | |
| SCHEMBL23254961 | 0.81 | TPSAB1 (0.61) | SMN1; SMN2CYP2C19CYP2C9CYP1A2TSHR | |
| SCHEMBL20289377 | 0.81 | TGM2 (0.54) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1709264 | 0.81 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2CYP2C19CYP2C9 | |
| SCHEMBL16357712 | 0.81 | HDAC6 (0.46) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2098729 | 0.81 | EPHX2 (0.44) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2250967 | 0.81 | EPHX2 (0.51) | SMN1; SMN2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772034-A | Preparation process of 2-p-chlorophenyl-5- (trifluoromethyl) pyrrole-3-nitrile | 山东亿嘉农化有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-117586167-A | New synthesis process of chlorfenapyr | 山东潍坊双星农药有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-118772034-A | Preparation process of 2-p-chlorophenyl-5- (trifluoromethyl) pyrrole-3-nitrile | 山东亿嘉农化有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118772034-A | Preparation process of 2-p-chlorophenyl-5- (trifluoromethyl) pyrrole-3-nitrile | 山东亿嘉农化有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117586167-A | New synthesis process of chlorfenapyr | 山东潍坊双星农药有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586167-A | New synthesis process of chlorfenapyr | 山东潍坊双星农药有限公司 | 2024-02-23 | — | — | CN | disclosed |
| EP-0531702-B1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-subst. -5-(trifluoromethyl)pyrrole compounds from N-(subst. benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | BASF AG (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-0531702-A1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substitued-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5145986-A | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoro-acetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1992-09-08 | — | — | US | disclosed |