Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767445 | 0.86 | CRBN (0.42) | CRBNALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7765802 | 0.81 | CRBN (0.54) | CRBNMMP1MMP9DAOGLA | |
| SCHEMBL7767450 | 0.72 | CRBN (0.41) | CRBNALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7765877 | 0.72 | MMP1 (0.46) | CRBNMMP1MMP9ALDH1A1MMP3 | |
| SCHEMBL7762208 | 0.72 | MMP1 (0.46) | CRBNMMP1MMP9ALDH1A1MMP3 | |
| SCHEMBL7764881 | 0.72 | MMP1 (0.46) | CRBNMMP1MMP9ALDH1A1MMP3 | |
| SCHEMBL23997552 | 0.68 | GLA (0.40) | CRBNMMP1MMP9DAOGLA | |
| SCHEMBL6447329 | 0.68 | GLA (0.40) | CRBNMMP1MMP9DAOGLA | |
| SCHEMBL7762186 | 0.66 | POLB (0.41) | CRBNDAOALDH1A1MMP13GAA | |
| SCHEMBL9196423 | 0.66 | CRBN (0.50) | CRBNMMP1MMP9ALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |