Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | NMT2 | O60551 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680958 | 0.92 | GPR35 (0.70) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL7771432 | 0.87 | MAOB (0.46) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL9246335 | 0.85 | GPR35 (0.84) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL10307303 | 0.82 | TDP1 (0.59) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11178199 | 0.81 | GPR35 (0.54) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL14544412 | 0.80 | GPR35 (0.65) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11537956 | 0.78 | GPR35 (0.63) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL116724 | 0.78 | GPR35 (0.72) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11209178 | 0.78 | MAOB (0.56) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL116708 | 0.77 | GPR35 (0.73) | GPR35LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |