Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | NMT2 | O60551 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307303 | 0.82 | TDP1 (0.59) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL11209177 | 0.81 | MAOB (0.55) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL9246335 | 0.80 | GPR35 (0.84) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL7767608 | 0.78 | GPR35 (0.60) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL11208927 | 0.78 | GPR35 (0.86) | GPR35TDP1LMNAMEN1KMT2A | |
| SCHEMBL14544412 | 0.77 | GPR35 (0.65) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL11537956 | 0.76 | GPR35 (0.63) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL18085022 | 0.74 | GPR35 (0.50) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL116724 | 0.73 | GPR35 (0.72) | MAOBMAOAGPR35TDP1LMNA | |
| SCHEMBL10517239 | 0.73 | MAOB (0.63) | MAOBMAOAGPR35TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017578-B1 | 5-(2-HYDROXY-3-THIOPROPOXY)-CHROMON-2-CARBOXYLIC ACIDS, THEIR SALTS AND ESTERS, PROCESS FOR THEIR PREPARATION AND MEDICINES | SANOFI S.A. (FR) | 1983-03-23 | — | — | EP | disclosed |
| US-4282247-A | ANTIANAPHYLACTIC, ANTIALLERGENIC | CM INDUSTRIES (FR) | 1981-08-04 | — | — | US | disclosed |
| EP-0017578-A1 | 5-(2-Hydroxy-3-thiopropoxy)-chromon-2-carboxylic acids, their salts and esters, process for their preparation and medicines | SANOFI S.A. (FR) | 1980-10-15 | — | — | EP | disclosed |