SCHEMBL776776

SCHEMBL776776

CCO[Si](C)(CC1CNCCO1)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 11/20 0.46
SLC6A4 P31645 10/20 0.46
SLC6A3 Q01959 10/20 0.46
HTR2A P28223 4/20 0.46
HTR2B P41595 2/20 0.46
ADRB2 P07550 2/20 0.46
HTR1A P08908 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA2C P18825 1/20 0.39
OPRK1 P41145 2/20 0.32
HRH1 P35367 1/20 0.32
OPRD1 P41143 1/20 0.32
HTR3A P46098 1/20 0.32
MLNR O43193 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2C P28335 1/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2409155 0.86 SLC6A4 (0.46) SLC6A2SLC6A4SLC6A3HTR2AHTR2B
SCHEMBL776321 0.81 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3HTR2AHTR2B
SCHEMBL776375 0.75 ADRA2C (0.44) SLC6A2SLC6A4SLC6A3HTR2AHTR2B
SCHEMBL773898 0.74 SLC6A4 (0.42) SLC6A2SLC6A4SLC6A3HTR2AHTR2B
SCHEMBL16714747 0.74 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3HTR2AHTR2B
SCHEMBL28862352 0.73 SLC6A4 (0.41) SLC6A2SLC6A4SLC6A3HTR2AHTR2B
Fluoride SCHEMBL7750151 0.73
SCHEMBL322796 0.73
SCHEMBL12524834 0.73
SCHEMBL3168 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758689-B2 Silver nanoparticle inks comprising aminomethylsilanes XEROX CORPORATION (US) 2017-09-12 US claimed
US-9758689-B2 Silver nanoparticle inks comprising aminomethylsilanes XEROX CORPORATION (US) 2017-09-12 US disclosed
US-20160108271-A1 SILVER NANOPARTICLE INKS COMPRISING AMINOMETHYLSILANES XEROX CORPORATION 2016-04-21 US disclosed
US-8361176-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2013-01-29 US disclosed
EP-1907517-B1 AMINE TUNGSTATES AND DIARYLAMINES IN LUBRICANT COMPOSITIONS KING INDUSTRIES INC (US) 2012-12-05 EP disclosed
US-8304023-B2 coating with a condensation-curable organopolysiloxanes with silanes to form elastomeric films insoluble in toluene; formed layer has a permanent soft hand and good bulk, no yellowing, free of volatile organic compounds; storage stability, solvent-free WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
US-20120066980-A1 Hydrophilic and Hydrophobic Silane Surface Modification of Abrasive Grains SAINT-GOBAIN ABRASIFS (FR) 2012-03-22 US disclosed
US-8080500-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2011-12-20 US disclosed
US-8021449-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2011-09-20 US disclosed
EP-2364241-A2 HYDROPHILIC AND HYDROPHOBIC SILANE SURFACE MODIFICATION OF ABRASIVE GRAINS Saint-Gobain Abrasives, Inc. (US) 2011-09-14 EP disclosed
US-7820602-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2010-10-26 US disclosed
US-20090260297-A1 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIFS (FR) 2009-10-22 US disclosed
WO-2009129384-A2 HYDROPHILIC AND HYDROPHOBIC SILANE SURFACE MODIFICATION OF ABRASIVE GRAINS SAINT-GOBAIN ABRASIVES, INC. (US) 2009-10-22 WO disclosed
US-20090029888-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. 2009-01-29 US disclosed
US-20080194440-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS RAVICHANDRAN RAMANATHAN 2008-08-14 US disclosed
US-20080107814-A1 Treatment Of Fiberfill Fibers With Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
EP-1773920-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2007-04-18 EP disclosed
US-20070042917-A1 Amine Tungstates and Lubricant Compositions KING INDUSTRIES, INC. 2007-02-22 US disclosed
WO-2006015740-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2006-02-16 WO disclosed