Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 13/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035846 | 0.88 | LSS (0.43) | LSSMEN1KMT2AKDM4ELMNA | |
| SCHEMBL8035571 | 0.86 | LSS (0.52) | LSSMEN1KMT2AKDM4E | |
| SCHEMBL7771989 | 0.83 | LSS (0.48) | LSSMEN1KMT2AKDM4ELMNA | |
| SCHEMBL3669374 | 0.82 | LSS (0.44) | LSSMEN1KMT2AKDM4ELMNA | |
| SCHEMBL8047705 | 0.82 | PPARD (0.38) | LSSKDM4ELMNAPPARDMAPK1 | |
| SCHEMBL7688254 | 0.81 | LSS (0.39) | LSSMEN1KMT2APPARDMAPK1 | |
| SCHEMBL7688257 | 0.81 | LSS (0.39) | LSSMEN1KMT2APPARDMAPK1 | |
| SCHEMBL8035630 | 0.80 | LSS (0.60) | LSSMEN1KMT2ALMNAPPARD | |
| SCHEMBL7688154 | 0.79 | LSS (0.52) | LSSMEN1KMT2A | |
| SCHEMBL7771940 | 0.79 | LSS (0.52) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |