Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.76 |
| ▸ | DRD3 | P35462 | 13/20 | 0.76 |
| ▸ | DRD4 | P21917 | 9/20 | 0.76 |
| ▸ | HTR1A | P08908 | 6/20 | 0.76 |
| ▸ | HTR2A | P28223 | 3/20 | 0.76 |
| ▸ | HTR2C | P28335 | 3/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.74 |
| ▸ | DRD1 | P21728 | 2/20 | 0.74 |
| ▸ | HTR2B | P41595 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7762657 | 0.99 | DRD2 (0.75) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7342827 | 0.94 | DRD2 (0.81) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7766329 | 0.87 | DRD3 (0.89) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL3080386 | 0.86 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7535217 | 0.86 | DRD2 (0.73) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7762622 | 0.86 | DRD3 (0.88) | DRD2DRD3DRD4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7765350 | 0.86 | DRD2 (0.98) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL7769953 | 0.85 | DRD2 (0.75) | DRD2DRD3DRD4HTR1AHTR2A | |
| Bp-897 SCHEMBL2125882 | 0.85 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AHTR2A | |
| Bp-897 SCHEMBL29382551 | 0.85 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873329-B1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2001-06-06 | — | — | EP | claimed |