Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772143 | 0.89 | TUBB4A (0.44) | TSHRCYP3A4NFKB1NPSR1GAA | |
| SCHEMBL29359121 | 0.87 | PPARG (0.46) | TSHRNPSR1ACHEALOX12 | |
| SCHEMBL3649536 | 0.87 | PPARG (0.46) | TSHRNPSR1ACHEALOX12 | |
| SCHEMBL14539690 | 0.78 | TSHR (0.58) | TSHRCYP3A4NFKB1SLC22A3BLM | |
| SCHEMBL30474606 | 0.76 | TSHR (0.59) | TSHRCYP3A4NFKB1SLC22A3BLM | |
| SCHEMBL14515694 | 0.76 | TSHR (0.59) | TSHRCYP3A4NFKB1SLC22A3BLM | |
| SCHEMBL29191830 | 0.75 | CYP3A4 (0.51) | TSHRCYP3A4NFKB1SLC22A3BLM | |
| SCHEMBL7775729 | 0.75 | ALDH1A1 (0.40) | NPSR1GAA | |
| SCHEMBL7773862 | 0.72 | PPARG (0.44) | TSHRNPSR1ACHEALOX12 | |
| SCHEMBL7767980 | 0.72 | PPARG (0.48) | TSHRNPSR1ACHEALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939749-B1 | PROCESS FOR THE PREPARATION OF BENZYL-ETHERS | AGRO CHEMIE NOEVENYVEDOESZER G (HU) | 2001-07-18 | — | — | EP | disclosed |