Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768115 | 1.00 | CHRNB2 (0.37) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7767874 | 0.85 | CHRNB2 (0.36) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7767876 | 0.85 | CHRNB2 (0.36) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL3672651 | 0.84 | CHRNB2 (0.38) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7636278 | 0.84 | CHRNB2 (0.40) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7669094 | 0.84 | ALDH1A1 (0.39) | ALDH1A1AGTR2DGAT1LMNA | |
| SCHEMBL7662056 | 0.84 | ALDH1A1 (0.39) | ALDH1A1AGTR2DGAT1LMNA | |
| Acetamiprid SCHEMBL26296 | 0.83 | ALDH1A1 (0.41) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| Acetamiprid SCHEMBL29352485 | 0.83 | ALDH1A1 (0.41) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| Acetamiprid SCHEMBL13448458 | 0.83 | ALDH1A1 (0.41) | CHRNB2CHRNA4MEN1CHRNA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665222-B1 | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5633375-A | NONTOXIC TO HUMNAS, ANIMALS, FISH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5489603-A | CONTAINING NITROGEN HETEROCYCLIC RINGS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0493369-B1 | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0665222-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |