Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768178 | 0.82 | MAPT (0.57) | MAOBKMT2AMEN1ALDH1A1 | |
| SCHEMBL7764594 | 0.81 | MAPT (0.46) | MAOBKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL7772444 | 0.81 | MAPT (0.46) | MAOBKDM4EHDAC3KMT2AHPGD | |
| SCHEMBL7768170 | 0.79 | ALDH1A1 (0.47) | KDM4EHDAC3KMT2AHPGDMEN1 | |
| SCHEMBL7769386 | 0.74 | ALDH1A1 (0.53) | KMT2AHPGDALDH1A1DRD2DRD4 | |
| SCHEMBL7565657 | 0.73 | HTR1A (0.45) | KDM4EHDAC3KMT2AHPGDMEN1 | |
| SCHEMBL25974208 | 0.72 | HDAC8 (0.50) | KMT2AHPGDALDH1A1SMPD1HTT | |
| SCHEMBL24500604 | 0.72 | SMPD1 (0.70) | KMT2AMEN1ALDH1A1SMPD1MAPK1 | |
| SCHEMBL7567224 | 0.71 | POLB (0.48) | KDM4EHDAC3KMT2AMEN1ALDH1A1 | |
| SCHEMBL7768489 | 0.71 | HDAC3 (0.43) | KDM4EHDAC3KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929515-B1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CONSEILS DE RECH S SOC D (FR) | 2001-06-20 | — | — | EP | claimed |
| US-5998666-A | ANTIULCER, ANTISECRETORY AGENTS; ANTIEMITIC | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1999-12-07 | — | — | US | claimed |
| EP-0929515-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013337-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | claimed |