Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265614 | 0.85 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL9211911 | 0.82 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL4696621 | 0.81 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL27861510 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL23723512 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL31541248 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL30382371 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL134547 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL9539264 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATP53KMT2A | |
| Propachlor SCHEMBL1701162 | 0.76 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2LMNATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884304-B1 | Process for the preparation of F-(4-Fluoro-phenyl)-N-isopropyl-chloracetamide | BAYER AG (DE) | 2001-07-04 | — | — | EP | disclosed |
| EP-0884304-A3 | Process for the preparation of F-(4-Fluoro-phenyl)-N-isopropyl-chloracetamide | BAYER AG (DE) | 1999-02-03 | — | — | EP | disclosed |
| EP-0884304-A2 | Process for the preparation of F-(4-Fluoro-phenyl)-N-isopropyl-chloracetamide | BAYER AG (DE) | 1998-12-16 | — | — | EP | disclosed |